Eight-day Inpatient Directly Observed Therapy for Antiretroviral Therapy (ART) Failure: A Tool For Preventing Unnecessary ART Changes and Optimizing Adherence Support
Author(s) -
Nicole Winchester,
Frank Maldarelli,
Yolanda Mejia,
Nicola Dee,
Robin Dewar,
Elizabeth Laidlaw,
Safia Kuriakose,
Pamela Stoll,
Michael A. Proschan,
H. Clifford Lane,
Alice K. Pau
Publication year - 2019
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciz590
Subject(s) - antiretroviral therapy , regimen , medicine , human immunodeficiency virus (hiv) , intensive care medicine , drug resistance , viral load , immunology , microbiology and biotechnology , biology
Eight-day inpatient directly observed therapy confirmed nonadherence as the major cause of virologic failure for 9 (45%) of 20 highly treatment-experienced persons with human immunodeficiency virus, extensive antiretroviral drug resistance, and high self-reported adherence rates, preventing unnecessary regimen changes.
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