Early Signals of Vaccine-driven Perturbation Seen in Pneumococcal Carriage Population Genomic Data
Author(s) -
Chrispin Chaguza,
Ellen Heinsbroek,
Rebecca A. Gladstone,
Terence Tafatatha,
Maaike Alaerts,
Chikondi Peno,
Jennifer Cornick,
Patrick Musicha,
Naor BarZeev,
Arox W. Kamng’ona,
Aras Kadioglu,
Lesley McGee,
William P. Hanage,
Robert F. Breiman,
Robert S. Heyderman,
Neil French,
Dean Everett,
Stephen D. Bentley
Publication year - 2019
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciz404
Subject(s) - carriage , serotype , streptococcus pneumoniae , biology , pneumococcal conjugate vaccine , population , pneumococcal disease , multilocus sequence typing , virology , antibiotic resistance , medicine , genetics , antibiotics , gene , genotype , environmental health , pathology
Pneumococcal conjugate vaccines (PCVs) have reduced pneumococcal diseases globally. Pneumococcal genomic surveys elucidate PCV effects on population structure but are rarely conducted in low-income settings despite the high disease burden.
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