Neutralizing and Neuraminidase Antibodies Correlate With Protection Against Influenza During a Late Season A/H3N2 Outbreak Among Unvaccinated Military Recruits
Author(s) -
Carol D. Weiss,
Wei Wang,
Yun Lu,
Monisha Billings,
Angelia A Eick-Cost,
Laura Couzens,
José L. Sánchez,
Anthony W. Hawksworth,
P Seguin,
Christopher A. Myers,
Richard A. Forshee,
Maryna C. Eichelberger,
Michael J. Cooper
Publication year - 2019
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciz1198
Subject(s) - neuraminidase , odds ratio , titer , medicine , outbreak , virology , immunology , pneumonia , antibody , antibody titer , hemagglutinin (influenza) , confidence interval , virus
Antibodies that inhibit hemagglutination have long been considered a correlate of protection against influenza, but these antibodies are only a subset of potentially protective antibodies. Neutralizing and neuraminidase antibodies may also contribute to protection, but data on their associations with protection are limited.
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