Long-acting Opioid Use and the Risk of Serious Infections: A Retrospective Cohort Study | Zendy

Andrew Wiese | Zendy; Marie R. Griffin | Zendy; William Schaffner | Zendy; Christoph Stein | Zendy; Robert A. Greevy | Zendy; Edward F. Mitchel | Zendy; Carlos G. Grijalva | Zendy

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Long-acting Opioid Use and the Risk of Serious Infections: A Retrospective Cohort Study

Author(s) -

Andrew Wiese,

Marie R. Griffin,

William Schaffner,

Christoph Stein,

Robert A. Greevy,

Edward F. Mitchel,

Carlos G. Grijalva

Publication year - 2018

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciy809

Subject(s) - medicine , oxycodone , opioid , retrospective cohort study , morphine , oxymorphone , cohort , rate ratio , confidence interval , receptor

Although evidence from animal and human studies indicates opioid analgesics increase susceptibility to infections, it is unclear whether the risk varies by specific opioid. We compared the risk of serious infection among patients initiating long-acting opioid analgesics with and without previously reported immunosuppressive properties.

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