The Impact of Intensive Versus Standard Anthelminthic Treatment on Allergy-related Outcomes, Helminth Infection Intensity, and Helminth-related Morbidity in Lake Victoria Fishing Communities, Uganda: Results From the LaVIISWA Cluster-randomized Trial | Zendy

Richard E. Sanya | Zendy; Gyaviira Nkurunungi | Zendy; Remy Hoek Spaans | Zendy; Margaret Nampijja | Zendy; Geraldine O’Hara | Zendy; Robert Kizindo | Zendy; Gloria Oduru | Zendy; Prossy Kabuubi Nakawungu | Zendy; Emmanuel Niwagaba | Zendy; Elson Abayo | Zendy; Joyce Kabagenyi | Zendy; Christopher Zziwa | Zendy; Josephine Tumusiime | Zendy; Esther Nakazibwe | Zendy; James Kaweesa | Zendy; Fred Muwonge Kakooza | Zendy; Mirriam Akello | Zendy; Lawrence Lubyayi | Zendy; Jaco J. Verweij | Zendy; Stephen Nash | Zendy; Ronald van Ree | Zendy; Harriet Mpairwe | Zendy; Edridah M. Tukahebwa | Zendy; Emily L. Webb | Zendy; Alison M. Elliott | Zendy; Barbara Nerima | Zendy; Lawrence Muhangi | Zendy; Helen Akurut | Zendy; Fatuma Nalukenge | Zendy; Beatrice Mirembe | Zendy; J Okello | Zendy; Sebastian Owilla | Zendy; Jonathan Levin | Zendy; Milly Namutebi | Zendy; Caroline Ninsiima | Zendy; Susan Amongi | Zendy; Grace Kamukama | Zendy; Susan Iwala | Zendy; Florence Akello | Zendy; Moses Sewankambo | Zendy; Denis Nsubuga | Zendy; Stephen Cose | Zendy; Linda J. Wammes | Zendy; Grace Kabami | Zendy; Eric Ssebagala | Zendy; Angela Nalwoga | Zendy; Dennison Kizito | Zendy; John Vianney Tushabe | Zendy; Jacent Nassuuna | Zendy; Serge A. Versteeg | Zendy; Edward Tumwesige | Zendy; Simon Mpooya | Zendy; David Abiriga | Zendy; Richard Walusimbi | Zendy; Victoria Nannozi | Zendy; Cynthia Kabonesa | Zendy; Moses Kizza | Zendy

Open Access

The Impact of Intensive Versus Standard Anthelminthic Treatment on Allergy-related Outcomes, Helminth Infection Intensity, and Helminth-related Morbidity in Lake Victoria Fishing Communities, Uganda: Results From the LaVIISWA Cluster-randomized Trial

Author(s) -

Richard E. Sanya,

Gyaviira Nkurunungi,

Remy Hoek Spaans,

Margaret Nampijja,

Geraldine O’Hara,

Robert Kizindo,

Gloria Oduru,

Prossy Kabuubi Nakawungu,

Emmanuel Niwagaba,

Elson Abayo,

Joyce Kabagenyi,

Christopher Zziwa,

Josephine Tumusiime,

Esther Nakazibwe,

James Kaweesa,

Fred Muwonge Kakooza,

Mirriam Akello,

Lawrence Lubyayi,

Jaco J. Verweij,

Stephen Nash,

Ronald van Ree,

Harriet Mpairwe,

Edridah M. Tukahebwa,

Emily L. Webb,

Alison M. Elliott,

Barbara Nerima,

Lawrence Muhangi,

Helen Akurut,

Fatuma Nalukenge,

Beatrice Mirembe,

J Okello,

Sebastian Owilla,

Jonathan Levin,

Milly Namutebi,

Caroline Ninsiima,

Susan Amongi,

Grace Kamukama,

Susan Iwala,

Florence Akello,

Moses Sewankambo,

Denis Nsubuga,

Stephen Cose,

Linda J. Wammes,

Grace Kabami,

Eric Ssebagala,

Angela Nalwoga,

Dennison Kizito,

John Vianney Tushabe,

Jacent Nassuuna,

Serge A. Versteeg,

Edward Tumwesige,

Simon Mpooya,

David Abiriga,

Richard Walusimbi,

Victoria Nannozi,

Cynthia Kabonesa,

Moses Kizza

Publication year - 2018

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciy761

Subject(s) - medicine , praziquantel , randomized controlled trial , schistosoma mansoni , deworming , albendazole , relative risk , hookworm infections , eggs per gram , schistosomiasis , immunology , confidence interval , helminthiasis , helminths , surgery

The prevalence of allergy-related diseases is increasing in low-income countries. Parasitic helminths, common in these settings, may be protective. We hypothesized that intensive, community-wide, anthelminthic mass drug administration (MDA) would increase allergy-related diseases, while reducing helminth-related morbidity.

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