A Prospective Multicenter Clinical Observational Study on Vancomycin Efficiency and Safety With Therapeutic Drug Monitoring | Zendy

Xiaoyu Liang | Zendy; Yaxing Fan | Zendy; Minjie Yang | Zendy; Jing Zhang | Zendy; Jufang Wu | Zendy; Jicheng Yu | Zendy; Jinhao Tao | Zendy; Guoping Lü | Zendy; Huifang Zhang | Zendy; Ruilan Wang | Zendy; Xiaoxing Wen | Zendy; Huayin Li | Zendy; Fengying Zhang | Zendy; Jingqin Hang | Zendy; Lihua Shen | Zendy; Zhongwei Zhang | Zendy; Qionghua Lin | Zendy; Fengming Fu | Zendy; Shengbin Wu | Zendy; Bo Shen | Zendy; Weifeng Huang | Zendy; Chunkang Chang | Zendy; Hong Zhang | Zendy; Qiwei Huang | Zendy; Yifan Shi | Zendy; Hong Ren | Zendy; Qing Yuan | Zendy; Xiaolian Song | Zendy; Xuming Luo | Zendy

Open Access

A Prospective Multicenter Clinical Observational Study on Vancomycin Efficiency and Safety With Therapeutic Drug Monitoring

Author(s) -

Xiaoyu Liang,

Yaxing Fan,

Minjie Yang,

Jing Zhang,

Jufang Wu,

Jicheng Yu,

Jinhao Tao,

Guoping Lü,

Huifang Zhang,

Ruilan Wang,

Xiaoxing Wen,

Huayin Li,

Fengying Zhang,

Jingqin Hang,

Lihua Shen,

Zhongwei Zhang,

Qionghua Lin,

Fengming Fu,

Shengbin Wu,

Bo Shen,

Weifeng Huang,

Chunkang Chang,

Hong Zhang,

Qiwei Huang,

Yifan Shi,

Hong Ren,

Qing Yuan,

Xiaolian Song,

Xuming Luo

Publication year - 2018

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciy680

Subject(s) - medicine , observational study , vancomycin , drug , intensive care medicine , therapeutic drug monitoring , multicenter study , pharmacology , randomized controlled trial , staphylococcus aureus , biology , bacteria , genetics

Vancomycin is a first-line antibiotic used for the treatment of severe gram-positive bacterial infections. Clinical guidelines recommend that the vancomycin trough concentration be 10-15 mg/L for regular infections and 15-20 mg/L for severe infections. We investigated whether increasing the vancomycin concentration would result in better clinical outcomes with sustainable adverse effects (AEs) in the Chinese population.

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