Carbapenem-resistant Isolates of theKlebsiella pneumoniaeComplex in Western China: The Common ST11 and the Surprising Hospital-specific Types
Author(s) -
Lu Liu,
Yu Feng,
Guping Tang,
Ji Lin,
Wenzhi Huang,
Fu Qiao,
Zhiyong Zong
Publication year - 2018
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciy662
Subject(s) - klebsiella pneumoniae , klebsiella , microbiology and biotechnology , enterobacteriaceae , china , biology , transmission (telecommunications) , medicine , gene , escherichia coli , genetics , geography , archaeology , engineering , electrical engineering
A genome sequence-based analysis of 74 carbapenem-resistant Klebsiella pneumoniae (CRKP) from 12 hospitals in Sichuan, China, revealed that the isolates carried blaKPC-2 (n = 48), blaNDM (n = 22), or blaIMP-4 (n = 4) were identified as K. pneumoniae (n = 67), Klebsiella variicola (n = 5), and Klebsiella quasipneumoniae (n = 2) and belonged to 19 sequence types. Both inter- and intrahospital transmission of multiple ST11 strains was identified. There is an urgent need for all hospitals in a given region to coordinate actions against CRKP.
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