Precision Surveillance for Viral Respiratory Pathogens: Virome Capture Sequencing for the Detection and Genomic Characterization of Severe Acute Respiratory Infection in Uganda | Zendy

Matthew J. Cummings | Zendy; Rafal Tokarz | Zendy; Barnabas Bakamutumaho | Zendy; John Kayiwa | Zendy; Timothy Byaruhanga | Zendy; Nicholas Owor | Zendy; Barbara Namagambo | Zendy; Allison Wolf | Zendy; Barun Mathema | Zendy; Julius J. Lutwama | Zendy; Neil W. Schluger | Zendy; W. Ian Lipkin | Zendy; Max R. O’Donnell | Zendy

Open Access

Precision Surveillance for Viral Respiratory Pathogens: Virome Capture Sequencing for the Detection and Genomic Characterization of Severe Acute Respiratory Infection in Uganda

Author(s) -

Matthew J. Cummings,

Rafal Tokarz,

Barnabas Bakamutumaho,

John Kayiwa,

Timothy Byaruhanga,

Nicholas Owor,

Barbara Namagambo,

Allison Wolf,

Barun Mathema,

Julius J. Lutwama,

Neil W. Schluger,

W. Ian Lipkin,

Max R. O’Donnell

Publication year - 2018

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciy656

Subject(s) - outbreak , public health surveillance , human virome , genotype , public health , respiratory infection , medicine , virology , biology , genome , respiratory system , genetics , gene , pathology

Precision public health is a novel set of methods to target disease prevention and mitigation interventions to high-risk subpopulations. We applied a precision public health strategy to syndromic surveillance for severe acute respiratory infection (SARI) in Uganda by combining spatiotemporal analytics with genomic sequencing to detect and characterize viral respiratory pathogens with epidemic potential.

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