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Characterization of Household and Community Shedding and Transmission of Oral Polio Vaccine in Mexican Communities With Varying Vaccination Coverage
Author(s) -
Jonathan Altamirano,
Natasha Purington,
Rasika Behl,
Clea Sarnquist,
Marisa Holubar,
Lourdes GarcíaGarcía,
Leticia Ferreyra-Reyes,
Rogelio Montero-Campos,
Luis Pablo CruzHervert,
Shanda Boyle,
John F. Modlin,
Christopher van Hoorebeke,
Sean Leary,
ChunHong Huang,
Marvin Sommer,
Elizabeth Ferreira-Guerrero,
Guadalupe Delgado-Sánchez,
Sergio CanizalesQuintero,
José Luis Díaz Ortega,
Manisha Desai,
Yvonne Maldonado
Publication year - 2018
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciy650
Subject(s) - vaccination , medicine , transmission (telecommunications) , polio vaccination , poliomyelitis , demography , environmental health , odds ratio , confidence interval , immunization , virology , immunology , electrical engineering , sociology , engineering , antigen
The World Health Assembly 2012 Polio Eradication and Endgame Strategic Plan calls for the eventual cessation of all oral polio vaccines (OPVs), to be replaced with inactivated polio vaccine (IPV); however, IPV induces less robust mucosal immunity than OPV. This study characterized household and community OPV shedding and transmission after OPV vaccination within primarily IPV-vaccinated communities.

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