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Assessing the Risk of Vaccine-derived Outbreaks After Reintroduction of Oral Poliovirus Vaccine in Postcessation Settings
Author(s) -
Rui Fu,
Jonathan Altamirano,
Clea Sarnquist,
Yvonne Maldonado,
Jason R. Andrews
Publication year - 2018
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciy605
Subject(s) - medicine , poliovirus , transmission (telecommunications) , poliomyelitis , outbreak , cohort , virology , poliomyelitis eradication , environmental health , vaccination , epidemiology , serotype , immunization , herd immunity , demography , immunology , virus , antibody , electrical engineering , sociology , engineering
The Polio Eradication and Endgame Strategic Plan 2013-2018 calls for the gradual withdrawal of oral poliovirus vaccine (OPV) from routine immunization. We aimed to quantify the transmission potential of Sabin strains from OPV when it is reintroduced, accidentally or deliberately, in a community vaccinated with inactivated poliovirus vaccine alone.

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