Does Simultaneous Administration of Bivalent (Types 1 and 3) Oral Poliovirus Vaccine and Inactivated Poliovirus Vaccine Induce Mucosal Cross-immunity to Poliovirus Type 2? | Zendy

Sonia Resik | Zendy; Alina Tejeda | Zendy; Ondrej Mach | Zendy; Magilé Fonseca | Zendy; Manuel Dı́az | Zendy; Nilda Alemañy | Zendy; Lai Heng Hung | Zendy; Yoan Alemán‬ | Zendy; Ileana Mesa | Zendy; Gloria Garcia | Zendy; Roland W. Sutter | Zendy

Open Access

Does Simultaneous Administration of Bivalent (Types 1 and 3) Oral Poliovirus Vaccine and Inactivated Poliovirus Vaccine Induce Mucosal Cross-immunity to Poliovirus Type 2?

Author(s) -

Sonia Resik,

Alina Tejeda,

Ondrej Mach,

Magilé Fonseca,

Manuel Dı́az,

Nilda Alemañy,

Lai Heng Hung,

Yoan Alemán‬,

Ileana Mesa,

Gloria Garcia,

Roland W. Sutter

Publication year - 2018

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciy604

Subject(s) - poliovirus , inactivated poliovirus vaccine , medicine , poliomyelitis , immunity , vaccination , excretion , poliomyelitis eradication , virology , enterovirus , intramuscular injection , immunology , virus , immune system

Inactivated poliovirus vaccine (IPV) alone does not induce mucosal immunity. However, it was hypothesized that administration of IPV together with bivalent (types 1+3) oral poliovirus vaccine (bOPV) may stimulate mucosal cross-immunity to poliovirus type 2 (PV2).

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