Antimicrobial Stewardship and Intensive Care Unit Mortality: A Systematic Review | Zendy

Patrick Lindsay | Zendy; Sagar Rohailla | Zendy; Linda R. Taggart | Zendy; David Lightfoot | Zendy; Thomas Havey | Zendy; Nick Daneman | Zendy; Christopher F. Lowe | Zendy; Matthew Muller | Zendy

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Antimicrobial Stewardship and Intensive Care Unit Mortality: A Systematic Review

Author(s) -

Patrick Lindsay,

Sagar Rohailla,

Linda R. Taggart,

David Lightfoot,

Thomas Havey,

Nick Daneman,

Christopher F. Lowe,

Matthew Muller

Publication year - 2018

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciy550

Subject(s) - medicine , antimicrobial stewardship , intensive care unit , intensive care medicine , confidence interval , relative risk , meta analysis , population , discontinuation , emergency medicine , medline , antibiotics , antibiotic resistance , environmental health , political science , law , microbiology and biotechnology , biology

Antimicrobial stewardship programs (ASPs) using audit and feedback in the intensive care unit (ICU) setting can reduce harms related to inappropriate antibiotic use. However, inappropriate discontinuation or narrowing of antibiotic treatment could increase infection-related mortality in this population. Individual ASP studies are underpowered to detect differences in mortality.

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