Ultrasensitive Human Immunodeficiency Virus Type 1 Viral Load as a Marker of Treatment Choice for Simplification Strategies
Author(s) -
Sidonie Lambert-Niclot,
Maxime Grudé,
JeanLuc Meynard,
AnneGeneviève Marcelin,
MarcAntoine Valantin,
Philippe Flandre,
Jacques Izopet,
Laëtitia Moinot,
Vincent Bouteloup,
Vincent Cálvez,
Christine Katlama,
PierreMarie Girard,
Laurence MorandJoubert
Publication year - 2018
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciy382
Subject(s) - medicine , virology , viral load , human immunodeficiency virus (hiv) , viral disease , virus , sida , lentivirus , immunology
Using 3 randomized Protease inhibitor (PI) monotherapy studies: Kalesolo, Dream and Monoi, we performed a pooled-analysis. Our objective was to determine in PI monotherapy and standard tritherapy: 1) distribution of ultrasensitive viral load (USVL) at week 96 (W96); 2) factors associated with virological failure (VF) at W96 and 3) factors associated with USVL<1 copy at W96.
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