MUC5AC Levels Associated With Respiratory Syncytial Virus Disease Severity | Zendy

Devi Rajan | Zendy; Evan L. O’Keefe | Zendy; Curtis Travers | Zendy; Courtney McCracken | Zendy; Sarah Geoghegan | Zendy; Mauricio T. Caballero | Zendy; Patricio L. Acosta | Zendy; Fernando P. Polack | Zendy; Larry J. Anderson | Zendy

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MUC5AC Levels Associated With Respiratory Syncytial Virus Disease Severity

Author(s) -

Devi Rajan,

Evan L. O’Keefe,

Curtis Travers,

Courtney McCracken,

Sarah Geoghegan,

Mauricio T. Caballero,

Patricio L. Acosta,

Fernando P. Polack,

Larry J. Anderson

Publication year - 2018

Publication title -

clinical infectious diseases

Language(s) - Uncategorized

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciy340

Subject(s) - medicine , biomarker , respiratory system , virus , disease , respiratory disease , severity of illness , immunology , lung , biochemistry , chemistry

To assess MUC5AC as a biomarker for respiratory syncytial virus (RSV) disease severity, we tested nasal aspirates from RSV+ children with mild, moderate, and severe disease. Levels were significantly higher in those in the severe and moderate groups compared to mild group, indicating MUC5AC may be a useful biomarker for RSV disease severity.

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