A 4.5-Year Within-Patient Evolution of a Colistin-Resistant Klebsiella pneumoniae Carbapenemase–Producing K. pneumoniae Sequence Type 258
Author(s) -
Agnès B. Jousset,
Rémy A. Bonnin,
Isabelle RosinskiChupin,
Delphine Girlich,
Gaëlle Cuzon,
Nicolas Cabanel,
Hélène Frech,
Éric Farfour,
Laurent Dortet,
Philippe Glaser,
Thierry Naas
Publication year - 2018
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciy293
Subject(s) - klebsiella pneumoniae , microbiology and biotechnology , colistin , biology , bacteremia , virulence , multilocus sequence typing , fimbria , carriage , streptococcus pneumoniae , medicine , genotype , gene , antimicrobial , genetics , escherichia coli , antibiotics , pathology
Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae (KPC-Kp) has emerged globally over the last decade as a major nosocomial pathogen that threatens patient care. These highly resistant bacteria are mostly associated with a single Kp clonal group, CG258, but the reasons for its host and hospital adaptation remain largely unknown.
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