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Cumulative Burden of Depression and All-Cause Mortality in Women Living With Human Immunodeficiency Virus
Author(s) -
Jon C. Mills,
Brian W. Pence,
Jonathan Todd,
Angela M. Bengtson,
Tiffany L. Breger,
Andrew Edmonds,
Robert L. Cook,
Adebola Adedimeji,
Rebecca M. Schwartz,
Seble Kassaye,
Joel Milam,
Jennifer Cocohoba,
Mardge H. Cohen,
Elizabeth T. Golub,
Gretchen N. Neigh,
Margaret A. Fischl,
MirjamColette Kempf,
Adaora A. Adimora
Publication year - 2018
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciy264
Subject(s) - medicine , interquartile range , depression (economics) , hazard ratio , confidence interval , proportional hazards model , center for epidemiologic studies depression scale , cumulative incidence , demography , cohort , psychiatry , depressive symptoms , anxiety , sociology , economics , macroeconomics
Research linking depression to mortality among people living with human immunodeficiency virus (PLWH) has largely focused on binary "always vs never" characterizations of depression. However, depression is chronic and is likely to have cumulative effects on mortality over time. Quantifying depression as a cumulative exposure may provide a better indication of the clinical benefit of enhanced depression treatment protocols delivered in HIV care settings.

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