Primaquine Pharmacokinetics in Lactating Women and Breastfed Infant Exposures | Zendy

Mary Ellen Gilder | Zendy; Warunee Hanpithakphong | Zendy; Richard M. Hoglund | Zendy; Joel Tärning | Zendy; Htun Htun Win | Zendy; Naw Hilda | Zendy; Cindy S. Chu | Zendy; Germana Bancone | Zendy; Verena I. Carrara | Zendy; Pratap Singhasiva | Zendy; Nicholas J. White | Zendy; François Nosten | Zendy; Rose McGready | Zendy

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Primaquine Pharmacokinetics in Lactating Women and Breastfed Infant Exposures

Author(s) -

Mary Ellen Gilder,

Warunee Hanpithakphong,

Richard M. Hoglund,

Joel Tärning,

Htun Htun Win,

Naw Hilda,

Cindy S. Chu,

Germana Bancone,

Verena I. Carrara,

Pratap Singhasiva,

Nicholas J. White,

François Nosten,

Rose McGready

Publication year - 2018

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciy235

Subject(s) - primaquine , medicine , breast milk , breastfeeding , malaria , plasmodium vivax , breast feeding , adverse effect , pharmacokinetics , obstetrics , pediatrics , infant formula , physiology , chloroquine , plasmodium falciparum , immunology , biology , biochemistry

Primaquine is the only drug providing radical cure of Plasmodium vivax malaria. It is not recommended for breastfeeding women as it causes hemolysis in glucose-6-phosphate dehydrogenase (G6PD)-deficient individuals, and breast milk excretion and thus infant exposure are not known.

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