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Prolonged Detection of Zika Virus Nucleic Acid Among Symptomatic Pregnant Women: A Cohort Study
Author(s) -
Matthew Lozier,
Eli S. Rosenberg,
Kate Doyle,
Laura E. Adams,
Liore Klein,
Jorge L. MuñozJordán,
Luisa I. Alvarado,
Tyler M. Sharp,
Gabriela PazBailey
Publication year - 2018
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciy209
Subject(s) - zika virus , medicine , cohort , prospective cohort study , cohort study , virus , pregnancy , virology , reverse transcription polymerase chain reaction , polymerase chain reaction , nucleic acid , obstetrics , biology , biochemistry , messenger rna , gene , genetics
A prospective cohort of women with reverse transcription polymerase chain reaction (RT-PCR) confirmed Zika virus infection aged 18–39 years in Puerto Rico found that pregnant women have about a 3-fold longer estimated median detection of Zika virus RNA in serum, which can increase definitive diagnosis of infection and facilitate timely and appropriate clinical management.

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