Diagnostic Accuracy of Clinical and Microbiological Signs in Patients With Skin Lesions Resembling Buruli Ulcer in an Endemic Region | Zendy

Miriam Eddyani | Zendy; Ghislain Emmanuel Sopoh | Zendy; Gilbert Adjimon Ayelo | Zendy; Luc Brun | Zendy; Jean-Jacques Roux | Zendy; Yves Thierry Barogui | Zendy; Dissou Affolabi | Zendy; William R. Faber | Zendy; Marleen Boelaert | Zendy; Annelies Van Rie | Zendy; Françoise Portaels | Zendy; Bouke C. de Jong | Zendy

Open Access

Diagnostic Accuracy of Clinical and Microbiological Signs in Patients With Skin Lesions Resembling Buruli Ulcer in an Endemic Region

Author(s) -

Miriam Eddyani,

Ghislain Emmanuel Sopoh,

Gilbert Adjimon Ayelo,

Luc Brun,

Jean-Jacques Roux,

Yves Thierry Barogui,

Dissou Affolabi,

William R. Faber,

Marleen Boelaert,

Annelies Van Rie,

Françoise Portaels,

Bouke C. de Jong

Publication year - 2018

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciy197

Subject(s) - buruli ulcer , medicine , dermatology , mycobacterium ulcerans , skin ulcer , endemic diseases , pathology , virology , disease

The diagnosis of the neglected tropical skin and soft tissue disease Buruli ulcer (BU) is made on clinical and epidemiological grounds, after which treatment with BU-specific antibiotics is initiated empirically. Given the current decline in BU incidence, clinical expertise in the recognition of BU is likely to wane and laboratory confirmation of BU becomes increasingly important. We therefore aimed to determine the diagnostic accuracy of clinical signs and microbiological tests in patients presenting with lesions clinically compatible with BU.

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