Predicting the Impact of Typhoid Conjugate Vaccines on Antimicrobial Resistance
Author(s) -
Samantha Kaufhold,
Reza Yaesoubi,
Virginia E. Pitzer
Publication year - 2019
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciy1108
Subject(s) - typhoid fever , antimicrobial , medicine , vaccination , antibiotic resistance , transmission (telecommunications) , salmonella enterica , salmonella typhi , salmonella , immunology , intensive care medicine , antibiotics , virology , biology , microbiology and biotechnology , bacteria , biochemistry , genetics , electrical engineering , escherichia coli , gene , engineering
Empiric prescribing of antimicrobials in typhoid-endemic settings has increased selective pressure on the development of antimicrobial-resistant Salmonella enterica serovar Typhi. The introduction of typhoid conjugate vaccines (TCVs) in these settings may relieve this selective pressure, thereby reducing resistant infections and improving health outcomes.
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