Utilization of Vector Autoregressive and Linear Transfer Models to Follow Up the Antibiotic Resistance Spiral in Gram-negative Bacteria From Cephalosporin Consumption to Colistin Resistance | Zendy

Hajnalka Tóth | Zendy; Adina Fésüs | Zendy; Orsolya Kungler-Gorácz | Zendy; Bence Balázs | Zendy; László Majoros | Zendy; Krisztina Szarka | Zendy; Gábor Kardos | Zendy

Open Access

Utilization of Vector Autoregressive and Linear Transfer Models to Follow Up the Antibiotic Resistance Spiral in Gram-negative Bacteria From Cephalosporin Consumption to Colistin Resistance

Author(s) -

Hajnalka Tóth,

Adina Fésüs,

Orsolya Kungler-Gorácz,

Bence Balázs,

László Majoros,

Krisztina Szarka,

Gábor Kardos

Publication year - 2018

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciy1086

Subject(s) - cephalosporin , medicine , colistin , microbiology and biotechnology , antibiotics , gram negative bacteria , antibiotic resistance , biology , genetics , escherichia coli , gene

Increasing antibiotic resistance may reciprocally affect consumption and lead to use of broader-spectrum alternatives; a vicious cycle that may gradually limit therapeutic options. Our aim in this study was to demonstrate this vicious cycle in gram-negative bacteria and show the utility of vector autoregressive (VAR) models for time-series analysis in explanatory and dependent roles simultaneously.

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