Determining the Origins of Human Immunodeficiency Virus Type 1 Drug-resistant Minority Variants in People Who Are Recently Infected Using Phylogenetic Reconstruction | Zendy

Jean L. Mbisa | Zendy; Peter Kirwan | Zendy; Anna Tostevin | Zendy; Juan Ledesma | Zendy; David Bibby | Zendy; Alison Brown | Zendy; Richard Myers | Zendy; Amin S. Hassan | Zendy; Gary Murphy | Zendy; David Asboe | Zendy; Anton Pozniak | Zendy; Stuart A. Kirk | Zendy; O Nöel Gill | Zendy; Caroline Sabin | Zendy; Valérie Delpech | Zendy; David Dunn | Zendy; Patricia Cane | Zendy; David Chadwick | Zendy; Duncan Churchill | Zendy; Duncan B. Clark | Zendy; Simon Collins | Zendy; Sam Douthwaite | Zendy; Esther Fearnhill | Zendy; Kholoud Porter | Zendy; Oliver Stirrup | Zendy; Christophe Fraser | Zendy; Anna María Geretti | Zendy; Rory Gunson | Zendy; Antony Hale | Zendy; Stéphane Hué | Zendy; Linda Lazarus | Zendy; Andrew Brown | Zendy; Tamyo Mbisa | Zendy; Nicola Mackie | Zendy; Chloe Orkin | Zendy; Eleni Nastouli | Zendy; Deenan Pillay | Zendy; Andrew Phillips | Zendy; Erasmus Smit | Zendy; Kate Templeton | Zendy; Peter Tilston | Zendy; Erik Volz | Zendy; Ian Williams | Zendy; Hongyi Zhang | Zendy; Keith Fairbrother | Zendy; Justine Dawkins | Zendy; Siobhan O’Shea | Zendy; Jane Mullen | Zendy; Alison Cox | Zendy; Richard D. Tandy | Zendy; Tracy Fawcett | Zendy; Mark Hopkins | Zendy; Clare Booth | Zendy; Ana Garcia Diaz | Zendy; Lynne Renwick | Zendy; Matthias L. Schmid | Zendy; Brendan Payne | Zendy; Jonathan Hubb | Zendy; Simon Dustan | Zendy; Amanda Bradley-Stewart | Zendy

Open Access

Determining the Origins of Human Immunodeficiency Virus Type 1 Drug-resistant Minority Variants in People Who Are Recently Infected Using Phylogenetic Reconstruction

Author(s) -

Jean L. Mbisa,

Peter Kirwan,

Anna Tostevin,

Juan Ledesma,

David Bibby,

Alison Brown,

Richard Myers,

Amin S. Hassan,

Gary Murphy,

David Asboe,

Anton Pozniak,

Stuart A. Kirk,

O Nöel Gill,

Caroline Sabin,

Valérie Delpech,

David Dunn,

Patricia Cane,

David Chadwick,

Duncan Churchill,

Duncan B. Clark,

Simon Collins,

Sam Douthwaite,

Esther Fearnhill,

Kholoud Porter,

Oliver Stirrup,

Christophe Fraser,

Anna María Geretti,

Rory Gunson,

Antony Hale,

Stéphane Hué,

Linda Lazarus,

Andrew Brown,

Tamyo Mbisa,

Nicola Mackie,

Chloe Orkin,

Eleni Nastouli,

Deenan Pillay,

Andrew Phillips,

Erasmus Smit,

Kate Templeton,

Peter Tilston,

Erik Volz,

Ian Williams,

Hongyi Zhang,

Keith Fairbrother,

Justine Dawkins,

Siobhan O’Shea,

Jane Mullen,

Alison Cox,

Richard D. Tandy,

Tracy Fawcett,

Mark Hopkins,

Clare Booth,

Ana Garcia Diaz,

Lynne Renwick,

Matthias L. Schmid,

Brendan Payne,

Jonathan Hubb,

Simon Dustan,

Amanda Bradley-Stewart

Publication year - 2018

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciy1048

Subject(s) - transmission (telecommunications) , phylogenetic tree , drug resistance , virology , mutation , virus , cluster (spacecraft) , medicine , clade , biology , genetics , gene , computer science , electrical engineering , programming language , engineering

Drug-resistant minority variants (DRMinVs) detected in patients who recently acquired human immunodeficiency virus type 1 (HIV-1) can be transmitted, generated de novo through virus replication, or technical errors. The first form is likely to persist and result in treatment failure, while the latter two could be stochastic and transient.

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