Prospective, Real-time Metagenomic Sequencing During Norovirus Outbreak Reveals Discrete Transmission Clusters | Zendy

Amanda M. Casto | Zendy; Amanda L. Adler | Zendy; Negar Makhsous | Zendy; Kristen Crawford | Zendy; Xuan Qin | Zendy; Jane Kuypers | Zendy; MeeiLi Huang | Zendy; Danielle M. Zerr | Zendy; Alexander L. Greninger | Zendy

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Prospective, Real-time Metagenomic Sequencing During Norovirus Outbreak Reveals Discrete Transmission Clusters

Author(s) -

Amanda M. Casto,

Amanda L. Adler,

Negar Makhsous,

Kristen Crawford,

Xuan Qin,

Jane Kuypers,

MeeiLi Huang,

Danielle M. Zerr,

Alexander L. Greninger

Publication year - 2018

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciy1020

Subject(s) - norovirus , outbreak , transmission (telecommunications) , medicine , metagenomics , caliciviridae , epidemiology , infection control , virology , intensive care medicine , biology , genetics , gene , electrical engineering , engineering

Norovirus outbreaks in hospital settings are a common challenge for infection prevention teams. Given the high burden of norovirus in most communities, it can be difficult to distinguish between ongoing in-hospital transmission of the virus and new introductions from the community, and it is challenging to understand the long-term impacts of outbreak-associated viruses within medical systems using traditional epidemiological approaches alone.

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