As-Needed Vs Immediate Etoposide Chemotherapy in Combination With Antiretroviral Therapy for Mild-to-Moderate AIDS-Associated Kaposi Sarcoma in Resource-Limited Settings: A5264/AMC-067 Randomized Clinical Trial | Zendy

Mina C. Hosseinipour | Zendy; Minhee Kang | Zendy; Susan E. Krown | Zendy; Aggrey Bukuru | Zendy; Triin Umbleja | Zendy; Jeffrey N. Martin | Zendy; Jackson Orem | Zendy; Catherine Godfrey | Zendy; Brenda Hoagland | Zendy; Noluthando Mwelase | Zendy; Deborah Langat | Zendy; Mulinda Nyirenda | Zendy; John D. MacRae | Zendy; Margaret Borok | Zendy; Wadzanai Samaneka | Zendy; Agnes Moses | Zendy; Rosie Mngqbisa | Zendy; Naftali Busakhala | Zendy; Otoniel Martı́nez-Maza | Zendy; Richard F. Ambinder | Zendy; Dirk P. Dittmer | Zendy; Mostafa Nokta | Zendy; Thomas Campbell | Zendy

Open Access

As-Needed Vs Immediate Etoposide Chemotherapy in Combination With Antiretroviral Therapy for Mild-to-Moderate AIDS-Associated Kaposi Sarcoma in Resource-Limited Settings: A5264/AMC-067 Randomized Clinical Trial

Author(s) -

Mina C. Hosseinipour,

Minhee Kang,

Susan E. Krown,

Aggrey Bukuru,

Triin Umbleja,

Jeffrey N. Martin,

Jackson Orem,

Catherine Godfrey,

Brenda Hoagland,

Noluthando Mwelase,

Deborah Langat,

Mulinda Nyirenda,

John D. MacRae,

Margaret Borok,

Wadzanai Samaneka,

Agnes Moses,

Rosie Mngqbisa,

Naftali Busakhala,

Otoniel Martı́nez-Maza,

Richard F. Ambinder,

Dirk P. Dittmer,

Mostafa Nokta,

Thomas Campbell

Publication year - 2018

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciy044

Subject(s) - medicine , etoposide , immune reconstitution inflammatory syndrome , randomized controlled trial , efavirenz , clinical trial , chemotherapy , sarcoma , emtricitabine , adverse effect , chemotherapy regimen , oncology , viral load , immunology , antiretroviral therapy , human immunodeficiency virus (hiv) , pathology

Mild-to-moderate AIDS-associated Kaposi sarcoma (KS) often responds to antiretroviral therapy (ART) alone; the role of chemotherapy is unclear. We assessed the impact of immediate vs as-needed oral etoposide (ET) among human immunodeficiency virus (HIV)-infected individuals with mild-to-moderate KS initiating ART.

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