Diagnostic and Prognostic Value of JC Virus DNA in Plasma in Progressive Multifocal Leukoencephalopathy | Zendy

Francesca Ferretti | Zendy; Arabella Bestetti | Zendy; Constantin T. Yiannoutsos | Zendy; Beverly Musick | Zendy; Simonetta Gerevini | Zendy; Laura Passeri | Zendy; Simona Bossolasco | Zendy; Antonio Boschini | Zendy; Diego Franciotta | Zendy; Adriano Lazzarin | Zendy; Paola Cinque | Zendy

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Diagnostic and Prognostic Value of JC Virus DNA in Plasma in Progressive Multifocal Leukoencephalopathy

Author(s) -

Francesca Ferretti,

Arabella Bestetti,

Constantin T. Yiannoutsos,

Beverly Musick,

Simonetta Gerevini,

Laura Passeri,

Simona Bossolasco,

Antonio Boschini,

Diego Franciotta,

Adriano Lazzarin,

Paola Cinque

Publication year - 2018

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciy030

Subject(s) - progressive multifocal leukoencephalopathy , medicine , jc virus , leukoencephalopathy , value (mathematics) , virology , virus , pathology , disease , statistics , mathematics

Progressive multifocal leukoencephalopathy (PML) is a severe demyelinating disease caused by the polyomavirus JC (John Cunningham; JCV) that affects patients with impaired immune systems. While JCV-DNA detection in cerebrospinal fluid (CSF) is diagnostic of PML, the clinical significance of plasma JCV-DNA is uncertain.

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