Emergence of Polyfunctional Cytotoxic CD4+ T Cells in Mycobacterium avium Immune Reconstitution Inflammatory Syndrome in Human Immunodeficiency Virus-Infected Patients | Zendy

Denise C. Hsu | Zendy; Kimberly F. Breglio | Zendy; Luxin Pei | Zendy; Chun-Shu Wong | Zendy; Bruno B. Andrade | Zendy; Virginia Sheikh | Zendy; Margery Smelkinson | Zendy; Constantinos Petrovas | Zendy; Adam Rupert | Zendy; Leonardo Gil-Santana | Zendy; Adrian M. Zelazny | Zendy; Steven M. Holland | Zendy; Kenneth N. Olivier | Zendy; Daniel L. Barber | Zendy; Irini Sereti | Zendy

Open Access

Emergence of Polyfunctional Cytotoxic CD4+ T Cells in Mycobacterium avium Immune Reconstitution Inflammatory Syndrome in Human Immunodeficiency Virus-Infected Patients

Author(s) -

Denise C. Hsu,

Kimberly F. Breglio,

Luxin Pei,

Chun-Shu Wong,

Bruno B. Andrade,

Virginia Sheikh,

Margery Smelkinson,

Constantinos Petrovas,

Adam Rupert,

Leonardo Gil-Santana,

Adrian M. Zelazny,

Steven M. Holland,

Kenneth N. Olivier,

Daniel L. Barber,

Irini Sereti

Publication year - 2018

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciy016

Subject(s) - medicine , cytotoxic t cell , immune system , immunology , virology , human immunodeficiency virus (hiv) , mycobacterium avium complex , immunopathology , virus , immunodeficiency , biology , in vitro , biochemistry

Immune reconstitution inflammatory syndrome (IRIS) is an aberrant inflammatory response in individuals with advanced human immunodeficiency virus (HIV) infection, after antiretroviral therapy (ART) initiation. The pathogenesis of Mycobacterium avium complex (MAC)-associated IRIS has not been fully elucidated.

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