Clinical Significance of Interferon-γ Neutralizing Autoantibodies Against Disseminated Nontuberculous Mycobacterial Disease | Zendy

Ami Aoki | Zendy; Takuro Sakagami | Zendy; Kazutaka Yoshizawa | Zendy; Kenjiro Shima | Zendy; Mio Toyama | Zendy; Yoshinari Tanabe | Zendy; Hiroshi Moro | Zendy; Nobumasa Aoki | Zendy; Satoshi Watanabe | Zendy; Toshiyuki Koya | Zendy; Takashi Hasegawa | Zendy; Kozo Morimoto | Zendy; Atsuyuki Kurashima | Zendy; Yoshihiko Hoshino | Zendy; Bruce C. Trapnell | Zendy; Toshiaki Kikuchi | Zendy

Open Access

Clinical Significance of Interferon-γ Neutralizing Autoantibodies Against Disseminated Nontuberculous Mycobacterial Disease

Author(s) -

Ami Aoki,

Takuro Sakagami,

Kazutaka Yoshizawa,

Kenjiro Shima,

Mio Toyama,

Yoshinari Tanabe,

Hiroshi Moro,

Nobumasa Aoki,

Satoshi Watanabe,

Toshiyuki Koya,

Takashi Hasegawa,

Kozo Morimoto,

Atsuyuki Kurashima,

Yoshihiko Hoshino,

Bruce C. Trapnell,

Toshiaki Kikuchi

Publication year - 2017

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cix996

Subject(s) - medicine , immunology , azithromycin , titer , nontuberculous mycobacteria , antibiotics , microbiology and biotechnology , mycobacterium , pathology , antibody , tuberculosis , biology

Interferon-γ neutralizing autoantibodies (nIFNγ-autoAbs) are reported in patients with disseminated nontuberculous mycobacteria (NTM) infection and may function by increasing the infection risk. Notwithstanding, the prevalence of nIFNγ-autoAbs as well as the clinical presentation, diagnosis, and natural history of disseminated NTM infection in these patients is poorly understood.

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