Genotype-Specific Measles Transmissibility: A Branching Process Analysis
Author(s) -
Sarah F. Ackley,
Jill K. Hacker,
Wayne Enanoria,
Lee Worden,
Seth Blumberg,
Travis C. Porco,
Jennifer Zipprich
Publication year - 2017
Publication title -
clinical infectious diseases
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cix974
Subject(s) - outbreak , measles , genotype , medicine , demography , confidence interval , vaccination , virology , statistics , veterinary medicine , biology , genetics , mathematics , sociology , gene
Substantial heterogeneity in measles outbreak sizes may be due to genotype-specific transmissibility. Using a branching process analysis, we characterize differences in measles transmission by estimating the association between genotype and the reproduction number R among postelimination California measles cases during 2000-2015 (400 cases, 165 outbreaks).
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