No Clinical Benefit of Empirical Antimicrobial Therapy for Pediatric Diarrhea in a High-Usage, High-Resistance Setting
Author(s) -
Vu Thuy Duong,
Ha Thanh Tuyen,
Pham Van Minh,
James I. Campbell,
Hoang Le Phuc,
Tran Do Hoang Nhu,
Le Thi Phuong Tu,
Tran Thi Hong Chau,
Le Thi Quynh Nhi,
Nguyễn Thanh Hùng,
Nguyễn Minh Ngọc,
Thi Thanh Huong Nguyen,
Lu Lan,
Corinne N. Thompson,
Guy Thwaites,
Ruklanthi de Alwis,
Stephen Baker
Publication year - 2017
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cix844
Subject(s) - medicine , antimicrobial , diarrhea , campylobacter , interquartile range , antibiotic resistance , shigella , intensive care medicine , salmonella , antibiotics , microbiology and biotechnology , biology , genetics , bacteria
Pediatric diarrheal disease presents a major public health burden in low- to middle-income countries. The clinical benefits of empirical antimicrobial treatment for diarrhea are unclear in settings that lack reliable diagnostics and have high antimicrobial resistance (AMR).
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