Identifying Immune Correlates of Protection Against Plasmodium falciparum Through a Novel Approach to Account for Heterogeneity in Malaria Exposure | Zendy

Aida Valmaseda | Zendy; Eusébio Macete | Zendy; Augusto Nhabomba | Zendy; Caterina Guinovart | Zendy; Pedro Aíde | Zendy; Azucena Bardají | Zendy; Quique Bassat | Zendy; Tacilta Nhampossa | Zendy; Sonia Maculuve | Zendy; Aina Casellas | Zendy; Llorenç Quintó | Zendy; Sergi Sanz | Zendy; Alfons Jiménez | Zendy; Gaoqian Feng | Zendy; Christine Langer | Zendy; Linda Reiling | Zendy; K. Sony Reddy | Zendy; Alok Pandey | Zendy; Chetan E. Chitnis | Zendy; Virander S. Chauhan | Zendy; Ruth Aguilar | Zendy; John J. Aponte | Zendy; Carlota Dobaño | Zendy; James G. Beeson | Zendy; Deepak Gaur | Zendy; Clara Menéndez | Zendy; Pedro L. Alonso | Zendy; Alfredo Mayor | Zendy

Open Access

Identifying Immune Correlates of Protection Against Plasmodium falciparum Through a Novel Approach to Account for Heterogeneity in Malaria Exposure

Author(s) -

Aida Valmaseda,

Eusébio Macete,

Augusto Nhabomba,

Caterina Guinovart,

Pedro Aíde,

Azucena Bardají,

Quique Bassat,

Tacilta Nhampossa,

Sonia Maculuve,

Aina Casellas,

Llorenç Quintó,

Sergi Sanz,

Alfons Jiménez,

Gaoqian Feng,

Christine Langer,

Linda Reiling,

K. Sony Reddy,

Alok Pandey,

Chetan E. Chitnis,

Virander S. Chauhan,

Ruth Aguilar,

John J. Aponte,

Carlota Dobaño,

James G. Beeson,

Deepak Gaur,

Clara Menéndez,

Pedro L. Alonso,

Alfredo Mayor

Publication year - 2017

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cix837

Subject(s) - malaria , plasmodium falciparum , medicine , immunology , immune system , plasmodium (life cycle) , virology , parasite hosting , world wide web , computer science

A main criterion to identify malaria vaccine candidates is the proof that acquired immunity against them is associated with protection from disease. The age of the studied individuals, heterogeneous malaria exposure, and assumption of the maintenance of a baseline immune response can confound these associations.

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