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Low Risk of Primary Clostridium difficile Infection With Tetracyclines: A Systematic Review and Metaanalysis
Author(s) -
Raseen Tariq,
Janice Cho,
Saloni Kapoor,
Robert Orenstein,
Siddharth Singh,
Darrell S. Pardi,
Sahil Khanna
Publication year - 2017
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cix833
Subject(s) - medicine , clostridium difficile , meta analysis , odds ratio , confidence interval , cohort study , antibiotics , relative risk , randomized controlled trial , medline , microbiology and biotechnology , biology , political science , law
The choice of antibiotics for systemic infections in patients with a high risk of Clostridium difficile infection (CDI) remains a clinical practice dilemma. Although some studies suggest that tetracyclines may be associated with a lower risk of CDI than other antibiotics, other results are conflicting. We conducted a systematic review and metaanalysis of studies that assessed the risk of CDI with tetracyclines compared to other antibiotics.

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