Open AccessDependency of Vaccine Efficacy on Preexposure and Age: A Closer Look at a Tetravalent Dengue Vaccine
Author(s) -
Yang Yang,
Ya Meng,
M. Elizabeth Halloran,
Ira M. Longini
Publication year - 2017
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cix766
Subject(s) - medicine , dengue vaccine , dengue virus , dengue fever , serotype , confidence interval , immunity , vaccine efficacy , immunology , vaccination , virology , immune system
A recombinant, live-attenuated, tetravalent dengue vaccine (CYD-TDV) was licensed for children aged ≥9 years in a few countries, but the dependence of vaccine efficacy on baseline immunity status and age groups has not been fully characterized.
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