Performance of Targeted Fungal Sequencing for Culture-Independent Diagnosis of Invasive Fungal Disease | Zendy

Carlos A. Gómez | Zendy; Indre Budvytiene | Zendy; Allison Zemek | Zendy; Niaz Banaei | Zendy

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Performance of Targeted Fungal Sequencing for Culture-Independent Diagnosis of Invasive Fungal Disease

Author(s) -

Carlos A. Gómez,

Indre Budvytiene,

Allison Zemek,

Niaz Banaei

Publication year - 2017

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cix728

Subject(s) - amplicon , internal transcribed spacer , amplicon sequencing , polymerase chain reaction , biology , biopsy , medicine , ribosomal rna , pathology , microbiology and biotechnology , gene , 16s ribosomal rna , genetics

Identification of fungi causing invasive fungal disease (IFD) is critical for guiding antifungal therapy. We describe the performance and clinical impact of a targeted panfungal polymerase chain reaction (PCR) amplicon sequencing assay for culture-independent diagnosis of IFD.

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