Influenza A(H5N1) Virus Infection in a Child With Encephalitis Complicated by Obstructive Hydrocephalus | Zendy

Gan C.K. Mak | Zendy; Mike Yat Wah Kwan | Zendy; Chris Ka Pun Mok | Zendy; Janice Y.C. Lo | Zendy; Malik Peiris | Zendy; Chi Wai Leung | Zendy

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Influenza A(H5N1) Virus Infection in a Child With Encephalitis Complicated by Obstructive Hydrocephalus

Author(s) -

Gan C.K. Mak,

Mike Yat Wah Kwan,

Chris Ka Pun Mok,

Janice Y.C. Lo,

Malik Peiris,

Chi Wai Leung

Publication year - 2017

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cix707

Subject(s) - hydrocephalus , virology , influenza a virus subtype h5n1 , medicine , virus , cerebrospinal fluid , encephalitis , viral encephalitis , influenza a virus , highly pathogenic , pathology , radiology

A 2-year-old boy with highly pathogenic avian influenza A(H5N1) virus infection with minimal respiratory symptoms developed encephalitis complicated by obstructive hydrocephalus. Viral RNA was detectable in cerebrospinal fluid. The virus belonged to H5N1 clade 2.3.2.1b and had acquired the mammalian adaptation mutation PB2 Q591K.

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