Distinguishing Secondary Dengue Virus Infection From Zika Virus Infection With Previous Dengue by a Combination of 3 Simple Serological Tests | Zendy

Wen-Yang Tsai | Zendy; HanHa Chai | Zendy; Carlos Brites | Zendy; JihJin Tsai | Zendy; Jasmine Tyson | Zendy; Célia Pedroso | Zendy; Jan Felix Drexler | Zendy; Mars Stone | Zendy; Graham Simmons | Zendy; Michael P. Busch | Zendy; Marion C. Lanteri | Zendy; Susan L. Stramer | Zendy; Ángel Balmaseda | Zendy; Eva Harris | Zendy; WeiKung Wang | Zendy

Open Access

Distinguishing Secondary Dengue Virus Infection From Zika Virus Infection With Previous Dengue by a Combination of 3 Simple Serological Tests

Author(s) -

Wen-Yang Tsai,

HanHa Chai,

Carlos Brites,

JihJin Tsai,

Jasmine Tyson,

Célia Pedroso,

Jan Felix Drexler,

Mars Stone,

Graham Simmons,

Michael P. Busch,

Marion C. Lanteri,

Susan L. Stramer,

Ángel Balmaseda,

Eva Harris,

WeiKung Wang

Publication year - 2017

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cix672

Subject(s) - zika virus , dengue fever , dengue virus , virology , serology , microcephaly , flavivirus , antibody dependent enhancement , virus , biology , immunology , medicine , antibody , pediatrics

The explosive spread of Zika virus (ZIKV) and associated microcephaly present an urgent need for sensitive and specific serodiagnostic tests, particularly for pregnant women in dengue virus (DENV)-endemic regions. Recent reports of enhanced ZIKV replication by dengue-immune sera have raised concerns about the role of previous DENV infection on the risk and severity of microcephaly and other ZIKV complications.

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