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Antibody Kinetics and Response to Routine Vaccinations in Infants Born to Women Who Received an Investigational Trivalent Group B Streptococcus Polysaccharide CRM197-Conjugate Vaccine During Pregnancy
Author(s) -
Shabir A. Madhi,
Anthonet Koen,
Clare Cutland,
Lisa Jose,
Niresha Govender,
Frederick Wittke,
Morounfolu Olugbosi,
Ajoke Sobanjo-ter Meulen,
Sherryl Baker,
Peter Dull,
Vas Narasimhan,
Karen S. Slobod
Publication year - 2017
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cix666
Subject(s) - medicine , diphtheria , vaccination , tetanus , pneumococcal conjugate vaccine , serotype , conjugate vaccine , diphtheria toxin , immunology , pneumococcal vaccine , immunization , pediatrics , antibody , streptococcus pneumoniae , microbiology and biotechnology , antibiotics , biology , toxin
Maternal vaccination against group B Streptococcus (GBS) might provide protection against invasive GBS disease in infants. We investigated the kinetics of transplacentally transferred GBS serotype-specific capsular antibodies in the infants and their immune response to diphtheria toxoid and pneumococcal vaccination.

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