Follow-up Blood Cultures in Gram-Negative Bacteremia: Are They Needed?
Author(s) -
Christi. Canzoneri,
Bobak Akhavan,
Zehra Tosur,
Pedro E Alcedo Andrade,
Gabriel M. Aisenberg
Publication year - 2017
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cix648
Subject(s) - medicine , bacteremia , blood culture , gram , gram negative bacterial infections , gram negative bacteria , intensive care medicine , microbiology and biotechnology , antibiotics , bacteria , biochemistry , chemistry , genetics , escherichia coli , gene , biology
Bloodstream infections remain a major cause of morbidity and mortality. Gram-negative bacilli (GNB) bacteremia is typically transient and usually resolves rapidly after the initiation of appropriate antibiotic therapy and source control. The optimal duration of treatment and utility of follow-up blood cultures (FUBC) have not been studied in detail. Currently, the management of gram-negative bacteremia is determined by clinical judgment. To investigate the value of repeat blood cultures, we analyzed 500 episodes of bacteremia to determine frequency of FUBC and identify risk factors for persistent bacteremia.
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