Systemic Inflammatory Response to Malaria During Pregnancy Is Associated With Pregnancy Loss and Preterm Delivery | Zendy

Michal Fried | Zendy; Jonathan D. Kurtis | Zendy; Bruce Swihart | Zendy; Sunthorn PondTor | Zendy; Amadou Barry | Zendy; Youssoufa Sidibé | Zendy; Santara Gaoussou | Zendy; Moussa Traoré | Zendy; Sekouba Keita | Zendy; Almahamoudou Mahamar | Zendy; Oumar Attaher | Zendy; Adama B. Dembele | Zendy; Kadidia B. Cisse | Zendy; Bacary S. Diarra | Zendy; Moussa B. Kanoute | Zendy; Alassane Dicko | Zendy; Patrick E. Duffy | Zendy

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Systemic Inflammatory Response to Malaria During Pregnancy Is Associated With Pregnancy Loss and Preterm Delivery

Author(s) -

Michal Fried,

Jonathan D. Kurtis,

Bruce Swihart,

Sunthorn PondTor,

Amadou Barry,

Youssoufa Sidibé,

Santara Gaoussou,

Moussa Traoré,

Sekouba Keita,

Almahamoudou Mahamar,

Oumar Attaher,

Adama B. Dembele,

Kadidia B. Cisse,

Bacary S. Diarra,

Moussa B. Kanoute,

Alassane Dicko,

Patrick E. Duffy

Publication year - 2017

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cix623

Subject(s) - medicine , pregnancy , cxcl9 , proinflammatory cytokine , chemokine , immunology , malaria , obstetrics , inflammation , cxcl10 , biology , genetics

Pregnancy malaria (PM) is associated with a proinflammatory immune response characterized by increased levels of cytokines and chemokines such as tumor necrosis factor-α, interferon-γ, interleukin 10 (IL-10), and CXCL9. These changes are associated with poor outcomes including low birthweight delivery and maternal anemia. However, it is unknown if inflammatory pathways during malaria are related to pregnancy loss and preterm delivery (PTD).

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