Human Cytomegalovirus–Specific Memory CD4+ T-Cell Response and Its Correlation With Virus Transmission to the Fetus in Pregnant Women With Primary Infection
Author(s) -
Chiara Fornara,
Irene Cassaniti,
Maurizio Zavattoni,
Milena Furione,
Kodjo Messan Guy Adzasehoun,
Annalisa De Silvestri,
Giuditta Comolli,
Fausto Baldanti
Publication year - 2017
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cix622
Subject(s) - medicine , cytomegalovirus , fetus , transmission (telecommunications) , pregnancy , human cytomegalovirus , cytomegalovirus infections , immunology , cytomegalovirus infection , virus , virology , correlation , obstetrics , herpesviridae , viral disease , biology , genetics , geometry , mathematics , electrical engineering , engineering
Primary human cytomegalovirus (HCMV) infection during pregnancy is the major cause of congenital viral sequelae. The HCMV-specific T-cell response may have a role in the prevention of virus transmission to the fetus.
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