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Predicting Resistance to Piperacillin-Tazobactam, Cefepime and Meropenem in Septic Patients With Bloodstream Infection Due to Gram-Negative Bacteria
Author(s) -
Cristina Vazquez Guillamet,
Rodrigo Vazquez Guillamet,
Scott T. Micek,
Marin H. Kollef
Publication year - 2017
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cix612
Subject(s) - cefepime , medicine , meropenem , piperacillin , tazobactam , chaid , antibiotic resistance , piperacillin/tazobactam , antibiotics , logistic regression , intensive care medicine , microbiology and biotechnology , imipenem , pseudomonas aeruginosa , decision tree , biology , bacteria , machine learning , genetics , computer science
Predicting antimicrobial resistance in gram-negative bacteria (GNB) could balance the need for administering appropriate empiric antibiotics while also minimizing the use of clinically unwarranted broad-spectrum agents. Our objective was to develop a practical prediction rule able to identify patients with GNB infection at low risk for resistance to piperacillin-tazobactam (PT), cefepime (CE), and meropenem (ME).

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