Open AccessShould We Be Testing for Baseline Integrase Resistance in Patients Newly Diagnosed With Human Immunodeficiency Virus?
Author(s) -
Yiannis Koullias,
Paul E. Sax,
Naomi F. Fields,
Rochelle P. Walensky,
Emily P. Hyle
Publication year - 2017
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cix542
Subject(s) - dolutegravir , medicine , integrase , virology , human immunodeficiency virus (hiv) , virus , antiretroviral therapy , viral load
Current guidelines recommend genotype resistance testing at diagnosis to guide initial selection of antiretroviral therapy (ART). Many standard resistance genotypes exclude testing for resistance to integrase inhibitors ("IR testing"), although this class of drugs is a component of most recommended first-line regimens.
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