Evidence of Ebola Virus Replication and High Concentration in Semen of a Patient During Recovery | Zendy

Kayla G. Barnes | Zendy; Jason Kindrachuk | Zendy; Aaron E. Lin | Zendy; Shirlee Wohl | Zendy; James Qu | Zendy; Samantha Tostenson | Zendy; William Dorman | Zendy; Michele Busby | Zendy; Katherine J. Siddle | Zendy; Cynthia Luo | Zendy; Christian B. Matranga | Zendy; Richard T. Davey | Zendy; Pardis C. Sabeti | Zendy; Daniel S. Chertow | Zendy

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Evidence of Ebola Virus Replication and High Concentration in Semen of a Patient During Recovery

Author(s) -

Kayla G. Barnes,

Jason Kindrachuk,

Aaron E. Lin,

Shirlee Wohl,

James Qu,

Samantha Tostenson,

William Dorman,

Michele Busby,

Katherine J. Siddle,

Cynthia Luo,

Christian B. Matranga,

Richard T. Davey,

Pardis C. Sabeti,

Daniel S. Chertow

Publication year - 2017

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cix518

Subject(s) - semen , ebola virus , virology , medicine , rna , virus , genome , viral replication , replication (statistics) , biology , andrology , genetics , gene

In one patient over time, we found that concentration of Ebola virus RNA in semen during recovery is remarkably higher than blood at peak illness. Virus in semen is replication-competent with no change in viral genome over time. Presence of sense RNA suggests replication in cells present in semen.

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