Does Disseminated Nontuberculous Mycobacterial Disease Cause False-Positive Determine TB-LAM Lateral Flow Assay Results? A Retrospective Review | Zendy

Jeremy Nel | Zendy; Christopher K. Lippincott | Zendy; Rebecca Berhanu | Zendy; David Spencer | Zendy; Ian Sanne | Zendy; Prudence Ive | Zendy

Open Access

Does Disseminated Nontuberculous Mycobacterial Disease Cause False-Positive Determine TB-LAM Lateral Flow Assay Results? A Retrospective Review

Author(s) -

Jeremy Nel,

Christopher K. Lippincott,

Rebecca Berhanu,

David Spencer,

Ian Sanne,

Prudence Ive

Publication year - 2017

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cix513

Subject(s) - medicine , coinfection , tuberculosis , nontuberculous mycobacteria , disease , retrospective cohort study , human immunodeficiency virus (hiv) , immunology , virology , pathology , mycobacterium

We retrospectively reviewed the Determine TB-LAM lateral flow assay (LF-LAM) results among human immunodeficiency virus-infected patients with disseminated nontuberculous mycobacterial (NTM) disease. LF-LAM was positive in 19 of 21 patients without evidence of tuberculosis (TB) coinfection. Although TB-NTM coinfection may have been underdiagnosed, our results suggest that disseminated NTM disease may cause false-positive LF-LAM results.

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