Reduced Frequency of Cells Latently Infected With Replication-Competent Human Immunodeficiency Virus-1 in Virally Suppressed Individuals Living in Rakai, Uganda | Zendy

Jessica L. Prodger | Zendy; Jun Lai | Zendy; Steven J. Reynolds | Zendy; Jeanne Keruly | Zendy; Richard D. Moore | Zendy; Jingo Kasule | Zendy; Taddeo Kityamuweesi | Zendy; Paul Buule | Zendy; David Serwadda | Zendy; Martha Nason | Zendy; Adam A. Capoferri | Zendy; Stephen F. Porcella | Zendy; Robert F. Siliciano | Zendy; Andrew D. Redd | Zendy; Janet D. Siliciano | Zendy; Thomas C. Quinn | Zendy

Open Access

Reduced Frequency of Cells Latently Infected With Replication-Competent Human Immunodeficiency Virus-1 in Virally Suppressed Individuals Living in Rakai, Uganda

Author(s) -

Jessica L. Prodger,

Jun Lai,

Steven J. Reynolds,

Jeanne Keruly,

Richard D. Moore,

Jingo Kasule,

Taddeo Kityamuweesi,

Paul Buule,

David Serwadda,

Martha Nason,

Adam A. Capoferri,

Stephen F. Porcella,

Robert F. Siliciano,

Andrew D. Redd,

Janet D. Siliciano,

Thomas C. Quinn

Publication year - 2017

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cix478

Subject(s) - virology , medicine , human immunodeficiency virus (hiv) , viral replication , virus , replication (statistics)

Human immunodeficiency virus type 1 (HIV-1) persists in latently infected resting CD4+ T cells (rCD4 cells), posing a major barrier to curing HIV-1 infection. Previous studies have quantified this pool of latently infected cells in Americans; however, no study has quantified this reservoir in sub-Saharan Africans, who make up the largest population of HIV-1-infected individuals globally.

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