Neurosyphilis Increases Human Immunodeficiency Virus (HIV)-associated Central Nervous System Inflammation but Does Not Explain Cognitive Impairment in HIV-infected Individuals With Syphilis | Zendy

Emily Ho | Zendy; Clare Maxwell | Zendy; Shelia B. Dunaway | Zendy; Sharon K. Sahi | Zendy; Lauren C. Tantalo | Zendy; Sheila A. Lukehart | Zendy; Christina M. Marra | Zendy

Open Access

Neurosyphilis Increases Human Immunodeficiency Virus (HIV)-associated Central Nervous System Inflammation but Does Not Explain Cognitive Impairment in HIV-infected Individuals With Syphilis

Author(s) -

Emily Ho,

Clare Maxwell,

Shelia B. Dunaway,

Sharon K. Sahi,

Lauren C. Tantalo,

Sheila A. Lukehart,

Christina M. Marra

Publication year - 2017

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cix473

Subject(s) - neurosyphilis , medicine , syphilis , immunology , treponema , cxcl10 , chemokine , inflammation , human immunodeficiency virus (hiv)

Individuals infected with human immunodeficiency virus (HIV) who have previously had syphilis may have cognitive impairment. We tested the hypothesis that neurosyphilis causes cognitive impairment in HIV by amplifying HIV-related central nervous system (CNS) inflammation.

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