Identifying Gaps in Respiratory Syncytial Virus Disease Epidemiology in the United States Prior to the Introduction of Vaccines
Author(s) -
Lindsay Kim,
Brian Rha,
Jon S. Abramson,
Larry J. Anderson,
Carrie L. Byington,
Grace Chen,
John P. DeVincenzo,
Kathryn M. Edwards,
Janet A. Englund,
Ann R. Falsey,
Marie R. Griffin,
Ruth A. Karron,
Karen G Martin,
H. Cody Meissner,
Flor M. Muñoz,
Andrew T. Pavia,
Pedro A. Piedra,
William Schaffner,
Eric A. F. Simões,
Rosalyn Singleton,
H. Keipp Talbot,
Edward E. Walsh,
Jane R. Zucker,
Susan I. Gerber
Publication year - 2017
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cix432
Subject(s) - medicine , epidemiology , respiratory tract infections , disease control , intensive care medicine , disease , family medicine , virology , immunology , pediatrics , respiratory system , psychiatry
Respiratory syncytial virus (RSV) causes lower respiratory tract illness frequently. No effective antivirals or vaccines for RSV are approved for use in the United States; however, there are at least 50 vaccines and monoclonal antibody products in development, with those targeting older adults and pregnant women (to protect young infants) in phase 2 and 3 clinical trials. Unanswered questions regarding RSV epidemiology need to be identified and addressed prior to RSV vaccine introduction to guide the measurement of impact and future recommendations. The Centers for Disease Control and Prevention (CDC) convened a technical consultation to gather input from external subject matter experts on their individual perspectives regarding evidence gaps in current RSV epidemiology in the United States, potential studies and surveillance platforms needed to fill these gaps, and prioritizing efforts. Participants articulated their individual views, and CDC staff synthesized individuals' input into this report.
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