The Immunogenicity of Fractional Intradermal Doses of the Inactivated Poliovirus Vaccine Is Associated With the Size of the Intradermal Fluid Bleb | Zendy

Jack Bibby | Zendy; Yauba Saidu | Zendy; Ama Umesi | Zendy; Ngozi Moneke-Anyanwoke | Zendy; Adedapo Olufemi Bashorun | Zendy; Mariama Badjie Hydara | Zendy; Ikechukwu Adigweme | Zendy; Jane U. Adetifa | Zendy; Michael Okoye | Zendy; Elishia Roberts | Zendy; Ralf Clemens | Zendy; Ananda S Bandyopadhyay | Zendy; Abdul Khalie Muhammad | Zendy; Sarah Mulwa | Zendy; Michael Royals | Zendy; Courtney Jarrahian | Zendy; David Jeffries | Zendy; Beate Kampmann | Zendy; Ed Clarke | Zendy

Open Access

The Immunogenicity of Fractional Intradermal Doses of the Inactivated Poliovirus Vaccine Is Associated With the Size of the Intradermal Fluid Bleb

Author(s) -

Jack Bibby,

Yauba Saidu,

Ama Umesi,

Ngozi Moneke-Anyanwoke,

Adedapo Olufemi Bashorun,

Mariama Badjie Hydara,

Ikechukwu Adigweme,

Jane U. Adetifa,

Michael Okoye,

Elishia Roberts,

Ralf Clemens,

Ananda S Bandyopadhyay,

Abdul Khalie Muhammad,

Sarah Mulwa,

Michael Royals,

Courtney Jarrahian,

David Jeffries,

Beate Kampmann,

Ed Clarke

Publication year - 2017

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cix381

Subject(s) - immunogenicity , intradermal injection , medicine , poliovirus , bleb (medicine) , virology , antibody , immunology , virus , ophthalmology , intraocular pressure , trabeculectomy

The immunogenicity of fractional (one-fifth, 0.1 mL) intradermal doses of the inactivated poliovirus vaccine (ID fIPV) is positively correlated with the size of the intradermal fluid bleb. Training of vaccinators for campaign and routine ID fIPV administration should focus on generating an 8- to 10-mm bleb with each injection. Clinical Trials Registration NCT01847872.

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