Adjunctive Corticosteroid Therapy in the Treatment of Coccidioidal Meningitis | Zendy

George R. Thompson | Zendy; Janis E. Blair | Zendy; Sharon Wang | Zendy; Robert Bercovitch | Zendy; Michael Bolaris | Zendy; Dane Van Den Akker | Zendy; Rodrigo López | Zendy; Arash Heidari | Zendy; Antonino Catanzaro | Zendy; José Cadena | Zendy; Peter ChinHong | Zendy; Brad Spellberg | Zendy; Royce H. Johnson | Zendy

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Adjunctive Corticosteroid Therapy in the Treatment of Coccidioidal Meningitis

Author(s) -

George R. Thompson,

Janis E. Blair,

Sharon Wang,

Robert Bercovitch,

Michael Bolaris,

Dane Van Den Akker,

Rodrigo López,

Arash Heidari,

Antonino Catanzaro,

José Cadena,

Peter ChinHong,

Brad Spellberg,

Royce H. Johnson

Publication year - 2017

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cix318

Subject(s) - medicine , corticosteroid , retrospective cohort study , adjunctive treatment , meningitis , cohort study , cohort , surgery

Coccidioidal meningitis (CM) has high morbidity, and adjunctive measures to improve outcomes are needed. Using an established multicenter retrospective cohort study of CM (N = 221), we found that patients receiving adjunctive corticosteroids had a significant reduction in secondary cerebrovascular events (P = .0049). Those with CM-associated cerebrovascular events (8%) may benefit from short-term corticosteroids.

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