A Novel Prosthetic Joint Infection Pathogen, Mycoplasma salivarium, Identified by Metagenomic Shotgun Sequencing | Zendy

Matthew Thoendel | Zendy; Patricio Jeraldo | Zendy; Kerryl E. GreenwoodQuaintance | Zendy; Nicholas Chia | Zendy; Matthew P. Abdel | Zendy; James M. Steckelberg | Zendy; Douglas R. Osmon | Zendy; Robin Patel | Zendy

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A Novel Prosthetic Joint Infection Pathogen, Mycoplasma salivarium, Identified by Metagenomic Shotgun Sequencing

Author(s) -

Matthew Thoendel,

Patricio Jeraldo,

Kerryl E. GreenwoodQuaintance,

Nicholas Chia,

Matthew P. Abdel,

James M. Steckelberg,

Douglas R. Osmon,

Robin Patel

Publication year - 2017

Publication title -

clinical infectious diseases

Language(s) - Uncategorized

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cix296

Subject(s) - metagenomics , shotgun sequencing , shotgun , medicine , pathogen , hypogammaglobulinemia , computational biology , microbiology and biotechnology , biology , virology , dna sequencing , immunology , gene , genetics , antibody

Defining the microbial etiology of culture-negative prosthetic joint infection (PJI) can be challenging. Metagenomic shotgun sequencing is a new tool to identify organisms undetected by conventional methods. We present a case where metagenomics was used to identify Mycoplasma salivarium as a novel PJI pathogen in a patient with hypogammaglobulinemia.

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