Specific Polysaccharide Antibody Deficiency Revealed by Severe Bacterial Infections in Adulthood: A Report on 11 Cases | Zendy

Benjamín López | Zendy; Anne Boucher | Zendy; Mathilde Bahuaud | Zendy; G. Mortuaire | Zendy; Hugues Melliez | Zendy; David Launay | Zendy; Louis Terriou | Zendy; Lidwine Wémeau-Stervinou | Zendy; B. Wallaert | Zendy; Karine Faure | Zendy; Florent Wallet | Zendy; É. Hachulla | Zendy; PierreYves Hatron | Zendy; Sylvain Dubucquoi | Zendy; Frédéric Batteux | Zendy; Myriam Labalette | Zendy; Guillaume Lefèvre | Zendy

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Specific Polysaccharide Antibody Deficiency Revealed by Severe Bacterial Infections in Adulthood: A Report on 11 Cases

Author(s) -

Benjamín López,

Anne Boucher,

Mathilde Bahuaud,

G. Mortuaire,

Hugues Melliez,

David Launay,

Louis Terriou,

Lidwine Wémeau-Stervinou,

B. Wallaert,

Karine Faure,

Florent Wallet,

É. Hachulla,

PierreYves Hatron,

Sylvain Dubucquoi,

Frédéric Batteux,

Myriam Labalette,

Guillaume Lefèvre

Publication year - 2017

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cix284

Subject(s) - medicine , antibody , context (archaeology) , immunology , polysaccharide , microbiology and biotechnology , biology , paleontology , biochemistry

We report on 11 cases of specific polysaccharide antibody deficiency (SPAD) revealed in adulthood by severe infections with encapsulated bacteria. Given that immunoglobulin replacement therapy can effectively prevent the recurrence of bacterial infections in this context, SPAD should be considered once other antibody deficiencies have been ruled out.

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